At a glance
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A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women With Stage 0, I, or II Breast Cancer
In Brief
A clinical study evaluating 3-dimensional conformal accelerated partial breast irradiation, brachytherapy, and 2 other interventions for Breast Cancer. Completed, enrolled 4,216 participants across 387 sites in 4 countries.
Detailed Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in different ways may kill any tumor cells that remain after surgery. It is not yet known whether whole breast radiation therapy is more effective than partial breast radiation therapy in treating breast cancer. PURPOSE: This randomized phase III trial is studying whole breast radiation therapy to see how well it works compared to partial breast radiation therapy in treating women who have undergone surgery for ductal carcinoma in situ or stage I or stage II breast cancer.
Study Details
Timeline
Interventions
Patients undergo radiation therapy once daily (days 1-5) for up to 7 weeks