CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 54 enrolled
Drug / intervention
Standard Cord Clamping +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01222364
NCT01222364Phase 2Completed
CompareCT.gov

Delayed Cord Clamping in VLBW Infants Pilot Study

NICHD Neonatal Research Network·interventional·Posted Oct 18, 2010·Updated Jun 17, 2026

In Brief

A Phase 2 clinical trial evaluating Standard Cord Clamping and Delayed Cord Clamping for Infant, Newborn and 3 related conditions. Completed, enrolled 54 participants across 4 sites.

Detailed Summary

This study tested the feasibility of conducting a randomized controlled trial to vary the timing that doctors clamp the umbilical cord after birth in extremely low birthweight infants. The study also tested whether delaying cord clamping by 30-35 seconds and holding the newborn approximately 10 inches below the birth canal would result in increased hematocrit at 4 hours of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
CountriesUnited States
CollaboratorsNational Center for Research Resources (NCRR)

Timeline

Phase 2CompletedFinished
2000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 18, 2010
Enrollment StartJun 1, 2000
Primary CompletionDec 1, 2000
TodayJul 1, 2026
Enrollment to primary: 6 monthsPosted 15.7 years ago

Interventions

Standard Cord Clampingprocedure

Immediate clamping (\<5 seconds) of the umbilical cord after delivery.

Delayed Cord Clampingprocedure

Clamping of the umbilical cord at 30-45 seconds after birth.