At a glance

ClinicalIndex Comparison Record

Phase 1Completed· 8 enrolled

Drug / intervention

Chlorogenic aciddrug

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02245204

NCT02245204Phase 1Completed

Compare CT.gov

Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers

Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd·interventional·Posted Sep 19, 2014·Updated Nov 21, 2018

In Brief

A Phase 1 clinical trial evaluating Chlorogenic acid for Advanced Cancer. Completed, enrolled 8 participants across 1 site.

Detailed Summary

The purpose of this study: Determining the Maximum Tolerated Dose (MTD), Dose-Limiting Toxicity (DLT), pharmacokinetics characteristic, and dosage regimen of phase II/III of Chlorogenic acid for injection in the advanced malignant tumor subjects;

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsAdvanced Cancer

CountriesChina

CollaboratorsPeking University Cancer Hospital & Institute

Timeline

Phase 1CompletedFinished

201520162017201820192020202120222023202420252026

Enrollment StartSep 2014

First PostedSep 2014

Primary CompletionOct 2016

TodayJul 2026

First PostedSep 19, 2014

Enrollment StartSep 1, 2014

Primary CompletionOct 1, 2016

TodayJul 1, 2026

Enrollment to primary: 2.1 yearsPosted 11.8 years ago

Interventions

Chlorogenic aciddrug

Chlorogenic acid for injection is polyphenols, micromolecular and un-endogenous substance. It might play the role of cancer treatment via balancing tumor micro-environmental immune status according to the stability and rationality of immunodeficiency and endogenous immune material expression around the tumor. Chlorogenic acid for injection is made from chlorogenic acid (purity≥98%) which is extracted from folium cortex eucommiae.Chlorogenic acid and its preparations have not been reported as chemical drug and marketed around the world.