At a glance
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Effects of Physical Activity Plus Short Course of Dexamethasone for Cancer-Related Fatigue in Advanced Cancer
In Brief
A Phase 3 clinical trial evaluating Dexamethasone, Exercise Intervention, and 3 other interventions for Advanced Malignant Neoplasm and 4 related conditions. Active but no longer recruiting, targeting 90 participants across 1 site.
Detailed Summary
This randomized phase II trial studies how well physical activity and dexamethasone work in reducing cancer-related fatigue in patients with cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced). Dexamethasone is approved for the treatment of tiredness, pain, and nausea. Physical activity may help improve cancer-related fatigue by improvement in symptoms, distress, and overall well-being. It is not yet known whether high dose or low dose dexamethasone combined with physical activity works better in reducing fatigue in patients with advanced cancer.
Study Details
Timeline
Interventions
Given PO
Complete a graded resistance exercise program and a walking regimen
Correlative studies
Ancillary studies
Ancillary studies