CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 186 enrolled
Drug / intervention
cisplatin and docetaxeldrug
Likely dose
cisplatin and docetaxel 75 mg/m2from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02575547
NCT02575547N/ACompleted
CompareCT.gov

Effect of Neoadjuvant Chemotherapy Followed by Concurrent Chemo-radiotherapy on Nutritional Status in Locoregionally Advanced Nasopharyngeal Carcinoma Patients: Prospective Observational Study

Zhao Chong·observational·Posted Oct 14, 2015·Updated Jul 30, 2020

In Brief

An observational study evaluating cisplatin and docetaxel for Nasopharyngeal Carcinoma and Malnutrition. Completed, enrolled 186 participants across 1 site.

Detailed Summary

This is an prospective，open-label, none-interventional, observational， multicenter phase II clinical trial. The purpose of this study is to observe the effect of neoadjuvant chemotherapy followed by concurrent chemoradiation therapy(CCRT) on nutritional status in locoregionally advanced nasopharyngeal carcinoma(NPC) patients, analyse the changes of patients' nutrition status during the treatment and the connection between nutrition changes and curative effects, evaluate nutritional risks under the neoadjuvant chemotherapy and CCRT and provide data and basis for further study。

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsNasopharyngeal Carcinoma, Malnutrition
CountriesChina
CollaboratorsWuhan University, Fudan University, Fujian Cancer Hospital, Zhejiang Cancer Hospital, First Affiliated Hospital of Guangxi Medical University, The First Affiliated Hospital of Xiamen University, Cancer Hospital of Guizhou Province, Hainan People's Hospital, First People's Hospital of Foshan

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedOct 14, 2015
Enrollment StartJun 1, 2015
Primary CompletionJan 1, 2020
Study CompletionJun 1, 2020
TodayJul 1, 2026
Enrollment to primary: 4.6 yearsPosted 10.7 years ago

Interventions

cisplatin and docetaxeldrug

NC：cisplatin 75 mg/m2 intravenous infusion in day1，docetaxel 75 mg/m2 intravenous infusion in day1，both drugs are given every 3 weeks, two courses. CCRT: intensity modulation radiation therapy(IMRT) and cisplatin (100mg/m2 on day 1) every three weeks for three\\three cycles during radiation therapy(RT). Dietary supplement: enteral nutrition and parenteral nutrition