CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 700 enrolled
Drug / intervention
dexmedetomidine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02809937
NCT02809937Phase 4Completed
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Impact of Dexmedetomidine on Long-term Outcome in Elderly Patients After Noncardiac Surgery: 3-year Follow-up of a Randomized Controlled Trial

Peking University First Hospital·interventional·Posted Jun 22, 2016·Updated Jun 16, 2017

In Brief

A Phase 4 clinical trial evaluating dexmedetomidine and placebo for Aged and 5 related conditions. Completed, enrolled 700 participants across 1 site.

Detailed Summary

Delirium is a frequent postoperative complication. Its occurrence is associated with worse long-term outcomes. In a previous randomized controlled trial, prophylactic low-dose dexmedetomidine infusion during the early postoperative period decreased the incidence of delirium in elderly patients after surgery. The purpose of this 3-year follow-up study is to evaluate whether prophylactic low-dose dexmedetomidine infusion can improve the 3-year outcome in elderly patients recruited in the previous randomized controlled trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAged, Surgical Procedures, Operative, Delirium, Dexmedetomidine, Mortality, Long-term Survivors
CountriesChina
CollaboratorsPeking University Third Hospital

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 22, 2016
Enrollment StartMay 1, 2011
Primary CompletionDec 1, 2016
Study CompletionJun 1, 2017
TodayJul 1, 2026
Enrollment to primary: 5.6 yearsPosted 10.0 years ago

Interventions

dexmedetomidinedrug

low-dose dexmedetomidine infusion

placebodrug

normal saline infusion