At a glance
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NCT03030495N/AActiveUpdate OverdueUpdated 13mo ago · Completion was 6mo agoIMaging and Physiologic Predictors of Atherosclerotic Progression in Deferred Lesions With Contemporary Medical Treatment Based on Fractional Flow Reserve-guided Strategy
In Brief
An observational study evaluating Comprehensive physiologic evaluation and Intravascular imaging devices for Ischemic Heart Disease. Active but no longer recruiting, targeting 1,400 participants across 4 sites.
Signals
Detailed Summary
1. To compare the risk of atherosclerotic lesion progression and subsequent patient-oriented composite outcomes (all-cause mortality, any MI, or any Ischemia-driven repeat revascularization) between deferred lesions with or without over microvascular disease, defined as physiological classification 2. To explore independent predictors of atherosclerotic lesion progression in deferred lesions based on fractional flow reserve-guided strategy and treated by contemporary medical treatment
Study Details
Timeline
Interventions
Comprehensive physiologic evaluation using pressure-temperature sensor wire to measure fractional flow reserve, coronary flow reserve, index of microcirculatory resistance
Intravascular ultrasound or optical coherence tomography