CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 90 enrolled
Drug / intervention
100% Oxygen +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03239678
NCT03239678N/ACompleted
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Safe Time for Apnea After Preoxygenation With Different Oxygen Concentration During the Induction of General Anesthesia

Sixth Affiliated Hospital, Sun Yat-sen University·interventional·Posted Aug 4, 2017·Updated Nov 29, 2022

In Brief

A clinical study evaluating 100% Oxygen, 30% Oxygen, and 4 other interventions for Anesthesia, General. Completed, enrolled 90 participants across 1 site.

Detailed Summary

The use of 100% oxygen during the induction of general anesthesia is always preferable to have enough time to secure the airway by endotracheal intubation, because preoxygenation with a low oxygen concentration may reduce the safe time for apnea. However, using a low oxygen concentration during preoxygenation might prevent the formation of atelectasis. There is still no clear conclusion about the best oxygen concentration for preoxygenation. Our study is designed to evaluate the safety of preoxygenation with 80%, 60%, 40%, 30% and 21% oxygen by the safe time for apnea during the induction of general anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnesthesia, General
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedAug 4, 2017
Enrollment StartAug 1, 2017
Primary CompletionDec 30, 2017
TodayJul 1, 2026
Enrollment to primary: 5 monthsPosted 8.9 years ago

Interventions

100% Oxygendrug

Conventional preoxygenation with 100% oxygen

30% Oxygendrug

preoxygenation with 30% oxygen

21% Oxygendrug

preoxygenation with 21% oxygen

40% Oxygendrug

preoxygenation with 40% oxygen

60% Oxygendrug

preoxygenation with 60% oxygen

80% Oxygendrug

preoxygenation with 80% oxygen