CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 15 enrolled
Drug / intervention
AZD3759drug
Likely dose
AZD3759 50mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03360929
NCT03360929Phase 2Completed

A Phase I/II, Open-label, Multi-center Study to Evaluate Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of AZD3759 in Chinese Patients With EGFRm+ NSCLC With Central Nervous System (CNS) Metastases

LYZZ Alpha Holding Ltd·interventional·Posted Dec 4, 2017·Updated Nov 25, 2022

In Brief

A Phase 2 clinical trial evaluating AZD3759 for Non Small Cell Lung Cancer. Completed, enrolled 15 participants across 4 sites.

Detailed Summary

This is a multi-center, open-label, dose escalation and phase I/II study, consisting of dose escalation in Part A and phase II study in Part B.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedDec 4, 2017
Enrollment StartOct 30, 2017
Primary CompletionNov 13, 2020
TodayJul 1, 2026
Enrollment to primary: 3.0 yearsPosted 8.6 years ago

Interventions

AZD3759drug

Strength: 50mg/tablet, 100mg/tablet Dosage and administration: Twice daily administration under fasting state.