CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 700 enrolled
Drug / intervention
dexmedetomidine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03436472
NCT03436472N/ACompleted
CompareCT.gov

Impact of Dexmedetomidine on Long-term Outcome in Elderly Patients After Noncardiac Surgery: 5-year Follow-up of a Randomized Controlled Trial

Peking University First Hospital·interventional·Posted Feb 19, 2018·Updated Jun 21, 2019

In Brief

A clinical study evaluating dexmedetomidine and placebo for Aged and 5 related conditions. Completed, enrolled 700 participants across 1 site.

Detailed Summary

Delirium is a frequent postoperative complication. Its occurrence is associated with worse long-term outcomes. In a previous randomized controlled trial, prophylactic low-dose dexmedetomidine infusion during the early postoperative period decreased the incidence of delirium in elderly patients after surgery. The purpose of this 5-year follow-up study is to evaluate whether prophylactic low-dose dexmedetomidine infusion can improve the 5-year outcomes in elderly patients recruited in the previous randomized controlled trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAged, Operative, Delirium, Dexmedetomidine, Mortality, Long-term Survivors
CountriesChina
CollaboratorsPeking University Third Hospital

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedFeb 19, 2018
Enrollment StartJun 1, 2017
Primary CompletionJan 8, 2019
Study CompletionApr 1, 2019
TodayJul 1, 2026
Enrollment to primary: 1.6 yearsPosted 8.4 years ago

Interventions

dexmedetomidinedrug

low-dose dexmedetomidine infusion

placebodrug

normal saline infusion