CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 67 enrolled
Drug / intervention
Weekly DP chemotherapy concurrent with thoracic radiotherapy +2 moredrug
Likely dose
Weekly DP chemotherapy concurrent with thoracic radiotherapy 25mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03673657
NCT03673657Phase 2Completed
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A Prospective, Single-arm, Phase II Study of Early Nutritional Intervention During Concurrent Chemoradiotherapy for Local Advanced Non-small Cell Lung Cancer

Sun Yat-sen University·interventional·Posted Sep 17, 2018·Updated Dec 8, 2023

In Brief

A Phase 2 clinical trial evaluating Early Nutrition Intervention from the start of CCRT, Thoracic radiotherapy, and 1 other intervention for Local Advanced Non-small Cell Lung Cancer. Completed, enrolled 67 participants across 1 site.

Detailed Summary

This single-arm phase II prospective study is to determine the efficacy of early nutritional intervention during concurrent chemoradiotherapy for local advanced non-small cell lung cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLocal Advanced Non-small Cell Lung Cancer
CountriesChina
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedSep 17, 2018
Enrollment StartAug 10, 2018
Primary CompletionMar 16, 2020
Study CompletionAug 31, 2023
TodayJul 1, 2026
Enrollment to primary: 1.6 yearsPosted 7.8 years ago

Interventions

Early Nutrition Intervention from the start of CCRTdietary

Nutrition counseling and oral nutritional supplements from the start of radiotherapy; weekly counseling sessions; daily energy intake of approximately 30 kcal/kg.

Thoracic radiotherapyradiation

Definitive thoracic radiotherapy with total radiation doses of 60-68 Gy

Weekly DP chemotherapy concurrent with thoracic radiotherapydrug

Weekly docetaxel (25mg/㎡) and nedaplatin (25mg/㎡) concurrent with thoracic radiotherapy