CI

At a glance

ClinicalIndex Comparison Record
Phase 1Unknown· 206 target
Drug / intervention
SHR-1701drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03710265
NCT03710265Phase 1Unknown

A Phase I, Open-label Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of SHR-1701 in Subjects With Metastatic or Locally Advanced Solid Tumors and Expansion to Selected Indications

Jiangsu HengRui Medicine Co., Ltd.·interventional·Posted Oct 18, 2018·Updated Nov 22, 2021

In Brief

A Phase 1 clinical trial evaluating SHR-1701 for Solid Tumor. Targeting 206 participants across 1 site.

Detailed Summary

The main purpose of this Phase I study is to access the safety and tolerability of SHR-1701 at different dose levels. It is hoped to find out the recommended dose for Phase II/III.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSolid Tumor
CountriesChina
Collaborators--

Timeline

Phase 1UnknownOverdue
20192020202120222023202420252026
First PostedOct 18, 2018
Enrollment StartNov 20, 2018
Primary CompletionDec 31, 2022
TodayJul 1, 2026
Enrollment to primary: 4.1 yearsPosted 7.7 years ago

Interventions

SHR-1701drug

Subjects will receive an intravenous infusion of SHR-1701 in a dose escalation until confirmed progression, unaccepted toxicity, or any criterion for withdrawal from the study.