At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Impact of Intraoperative Blood Pressure Management and Dexamethasone on Patient's Outcomes After Lung Cancer Surgery: A 2 × 2 Factorial Randomized Controlled Trial
In Brief
A clinical study evaluating Dexamethasone, Targeted blood pressure management, and 2 other interventions for Lung Cancer and 5 related conditions. Currently recruiting, targeting 1,988 participants across 1 site.
Detailed Summary
Surgery is the front-line therapy for non-small cell lung cancer (NSCLC) but postoperative complications remains high and patients' long-term outcome is still challenging. In addition to surgery, anesthetic management particularly intraoperative blood pressure management and use of dexamethasone may affect patients' early and long-term outcomes after surgery for NSCLC. This study aims to investigate the impact of intraoperative blood pressure management and dexamethasone administration on early and long-term outcomes in patients undergoing surgery for lung cancer.
Study Details
Timeline
Interventions
Dexamethasone (10 mg/2 ml) is administered before anesthesia induction.
Blood pressure is maintained within ±10% from baseline.
Placebo (2 ml normal saline) is administered before anesthesia induction.
Blood pressure is maintained according to routine practice.