CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 1,872 target
Drug / intervention
Angiography-derived FFR +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04397211
NCT04397211N/AActiveUpdate OverdueUpdated 29mo ago · Completion was 21mo ago
Enrollment Stalled
CompareCT.gov

Comparison of Angiography-derived Fractional FLow Reserve- And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients With CoRonary Artery Disease

Second Affiliated Hospital, School of Medicine, Zhejiang University·interventional·Posted May 21, 2020·Updated Jan 23, 2024

In Brief

A clinical study evaluating Angiography-derived FFR and IVUS for Coronary Artery Disease. Active but no longer recruiting, targeting 1,872 participants across 23 sites in 2 countries.

Signals

Enrollment appears stalled

Detailed Summary

Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Artery Disease
CountriesChina, South Korea
CollaboratorsSeoul National University Hospital, Affiliated Hangzhou First People's Hospital, Wuhan University, Peking University Third Hospital, The Affiliated Hospital of Hangzhou Normal University, RenJi Hospital, Second Hospital of Shanxi Medical University, First Affiliated Hospital of Wenzhou Medical University, Second Affiliated Hospital of Wenzhou Medical University, Changxing People's Hospital, The Affiliated Hospital of Medical College, Ningbo University, Jinhua Central Hospital, Shandong University of Traditional Chinese Medicine, Dongyang People's Hospital, The First Affiliated Hospital of Nanchang University, Jining First People's Hospital, Second Affiliated Hospital of Shantou University Medical College, Ulsan University Hospital, Huizhou Municipal Central Hospital, Zhejiang Greentown Cardiovascular Hospital, The Fourth People's Hospital of Jinan, First Affiliated Hospital of Kunming Medical University

Timeline

N/AActive
20212022202320242025202620272028
First PostedMay 21, 2020
Enrollment StartMay 29, 2020
Primary CompletionSep 1, 2024
Study CompletionSep 1, 2028
TodayJul 1, 2026
Enrollment to primary: 4.3 yearsPosted 6.1 years ago

Interventions

Angiography-derived FFRprocedure

The percutaneous coronary intervention using drug-eluting stent will be indicated according to following criteria in the Angiography-derived FFR-guided strategy arm \*Criteria for revascularization: Angiography-derived FFR ≤ 0.80

IVUSprocedure

The percutaneous coronary intervention using drug-eluting stent will be indicated according to following criteria in the IVUS-guided strategy arm \*Criteria for revascularization: Minimum lumen area (MLA) ≤ 3mm2 or 3\< MLA ≤ 4mm2 \& Plaque burden \> 70%