CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 50 target
Drug / intervention
cisplatin-based chemotherapydrug
Likely dose
cisplatin-based chemotherapy 80 mg/m2from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04544969
NCT04544969N/ARecruitingOn TrackUpdated 17mo ago
Long Recruiting

Detecting Chemosensitivity and Predicting Treatmemt Efficacy With Circulating Tumour Cells From Peripheral Blood in Metastatic Nasopharyngeal Carcinoma Patients

Sun Yat-sen University·observational·Posted Sep 10, 2020·Updated Jan 28, 2025

In Brief

An observational study evaluating cisplatin-based chemotherapy for Circulating Tumor Cell and 3 related conditions. Currently recruiting, targeting 50 participants across 1 site.

Detailed Summary

The prospective observational clinical study will recruit 50 metastatic nasopharyngeal carcinoma (mNPC) patients, detecting patient's chemosensitivity with the circulating tumor cells (CTCs) from peripheral blood and prdicting patient's treatment efficacy with CTCs dynamic change.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ARecruiting
20212022202320242025202620272028
First PostedSep 10, 2020
Enrollment StartApr 1, 2020
Primary CompletionDec 31, 2026
Study CompletionDec 31, 2027
TodayJul 1, 2026
Enrollment to primary: 6.8 yearsPosted 5.8 years agoPrimary completion in 6 months

Interventions

cisplatin-based chemotherapydrug

GP: cisplatin 80 mg/m2 intravenous infusion on day1, gemcitabine 1000 mg/m2 intravenous infusion on day 1 and 8, both drugs are given every 3 weeks, recommended 6 cycles. TP: cisplatin 75 mg/m2 intravenous infusion in day1, docetaxel 75 mg/m2 intravenous infusion in day 1, both drugs are given every 3 weeks, recommended 6 cycles. PF: cisplatin 100 mg/m2 intravenous infusion in day1, fluorouracil 4000 mg/m2 intravenous infusion in day 1 to 5, both drugs are given every 3 weeks, recommended 6 cycles. TPF: cisplatin 60 mg/m2 intravenous infusion in day1, docetaxel 60 mg/m2 intravenous infusion in day 1, fluorouracil 3000 mg/m2 intravenous infusion in day 1 to 5, both drugs are given every 3 weeks, recommended 6 cycles. Choice of chemotherapy regimen is decided by patient's doctor in charge.