CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 70 target
Drug / intervention
MRI +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

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NCT04586049N/AActiveOn Track
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Autonomic Dysfunction, Brain Blood Flow and Cognitive Decline in Veterans With Gulf War Illness

University of Wisconsin, Madison·observational·Posted Oct 14, 2020·Updated Jun 8, 2026

In Brief

An observational study evaluating MRI, Transcranial Doppler Ultrasound, and 1 other intervention for Brain Blood Flow and Neurovascular Control. Active but no longer recruiting, targeting 70 participants across 1 site.

Detailed Summary

Brain blood flow regulation and autonomic dysfunction will be measured in Veterans with and without Gulf War Illness who served in the Gulf War between 1990 and 1992.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Blood Flow, Neurovascular Control
CountriesUnited States
CollaboratorsUnited States Department of Defense

Timeline

N/AActive
2021202220232024202520262027
First PostedOct 14, 2020
Enrollment StartMay 16, 2023
Primary CompletionDec 1, 2026
TodayJul 1, 2026
Enrollment to primary: 3.5 yearsPosted 5.7 years agoPrimary completion in 5 months

Interventions

MRIdevice

Participants will undergo an MRI scan while participating in a breathing test to measure brain blood flow.

Transcranial Doppler Ultrasounddevice

Participants will undergo a TCD scan while participating in a breathing test to measure brain blood flow.

Sympathetic Nerve Activityother

Participants will undergo sympathetic nerve activity testing while participating in a breathing test.