CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Total body PET/CT (uExplorer)device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04654234
NCT04654234N/ACompleted
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Total-body PET/CT Imaging Using the uEXPLORER in Non-small Cell Lung Cancer Patients Treated by Induction Chemotherapy Plus Nivolumab and Definitive Concurrent Chemoradiotherapy

Sun Yat-sen University·observational·Posted Dec 4, 2020·Updated Jan 23, 2024

In Brief

An observational study evaluating Total body PET/CT (uExplorer) for Non-small Cell Lung Cancer. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The prospective study aims to explore the value of total-body PET/CT dynamic imaging (uExplorer) in assessing tumor metabolic heterogeneity and predicting prognosis for patients with locally advanced, unresectable non-small cell lung cancer (stage III) treated by neoadjuvant chemotherapy plus nivolumab and definitive concurrent chemoradiation therapy.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsNon-small Cell Lung Cancer
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedDec 4, 2020
Enrollment StartDec 1, 2020
Primary CompletionDec 30, 2023
TodayJul 1, 2026
Enrollment to primary: 3.1 yearsPosted 5.6 years ago

Interventions

Total body PET/CT (uExplorer)device

A total-body positron emission tomography/computed tomography (PET/CT) scanner (uEXPLORER) with a 192-cm scan range was applied for cancer diagnosis, organ function assessment and treatment outcome prediction. The total-body PET scanner can acquire scans with lower administered activity or short acquisition time, total-body dynamic acquisition at a longer delayed time point, and high detectability of exiguous changes of the whole body, and tumor as well.