CI

At a glance

ClinicalIndex Comparison Record
Phase 3Unknown· 266 target
Drug / intervention
BEAC +1 moredrug
Likely dose
BEAC 300 mg/m2from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04880746
NCT04880746Phase 3Unknown
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Efficacy and Safety of Cladribine Combined With BEAC ( Semustine, Etoposide, Cytarabine, Cyclophosphamide) Pretreatment Regimen in the Treatment of Peripheral T-cell Lymphoma: a Multicenter Clinical Study

Ruijin Hospital·interventional·Posted May 11, 2021·Updated May 11, 2021

In Brief

A Phase 3 clinical trial evaluating BEAC and Cladribine combined with BEAC for Peripheral T-cell Lymphoma. Targeting 266 participants across 1 site.

Detailed Summary

This multi-center clinical study will evaluate the efficacy and safety of Cladribine Combined With BEAC Pretreatment Regimen in the Treatment of Peripheral T-cell Lymphoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeripheral T-cell Lymphoma
CountriesChina
CollaboratorsXinqiao Hospital of Chongqing, The First Affiliated Hospital of Anhui Medical University, Harbin Hematology and Oncology Institute, Affiliated Zhongshan Hospital of Dalian University, Qilu Hospital of Shandong University, Fujian Medical University Union Hospital, Shanxi Province Cancer Hospital, RenJi Hospital, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Huashan Hospital

Timeline

Phase 3UnknownOverdue
202120222023202420252026
First PostedMay 11, 2021
Enrollment StartOct 17, 2020
Primary CompletionOct 17, 2024
Study CompletionOct 17, 2025
TodayJul 1, 2026
Enrollment to primary: 4 yearsPosted 5.1 years ago

Interventions

BEACdrug

Semustine, 300 mg/m2，-6d； Etoposide, 100 mg/m2，-5～-2d； Cytarabine, 100mg/m2，q12h，-5～-2d； Cyclophosphamide, 1.5g/m2，-5～-2d

Cladribine combined with BEACdrug

Cladribine, 6mg/m2，-5～-2d, two hours before Cytarabine Semustine, 300 mg/m2，-6d； Etoposide, 100 mg/m2，-5～-2d； Cytarabine, 100mg/m2，q12h，-5～-2d； Cyclophosphamide, 1.5g/m2，-5～-2d