CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 110 enrolled
Drug / intervention
Savolitinibdrug
Likely dose
Savolitinib 600 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04923932
NCT04923932Phase 2Completed

A Multi-center, Open-label, Phase II Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of Savolitinib in Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients With MET Gene Amplifications

Hutchison Medipharma Limited·interventional·Posted Jun 11, 2021·Updated May 12, 2026

In Brief

A Phase 2 clinical trial evaluating Savolitinib for Gastric Cancer and Esophagogastric Junction Disorder. Completed, enrolled 110 participants across 1 site.

Detailed Summary

Treating Gastric Cancer and Esophagogastric junction adenocarcinoma Patients with MET gene amplifications with Savolitinib

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedJun 11, 2021
Enrollment StartJul 27, 2021
Primary CompletionApr 21, 2026
TodayJul 1, 2026
Enrollment to primary: 4.7 yearsPosted 5.1 years ago

Interventions

Savolitinibdrug

Patients meeting the study inclusion criteria will receive Savolitinib \[Savolitinib 600 mg, po, once per day (QD) continuously in patients with baseline weight ≥50 kg, and Savolitinib 400 mg, po, QD in patients with baseline weight \<50 kg\] in 21 day treatment cycle, until disease progression, death, intolerable toxicity or other termination criteria as specified in the protocol, whichever occurs earliest.