CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,051 enrolled
Drug / intervention
Epidural analgesiadrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04940091
NCT04940091N/ACompleted
CompareCT.gov

Association Between the Effect of Epidural Analgesia and the Development of Maternal Fever During Labor: a Multicenter, Prospective, Observational, Cohort Study

Peking University First Hospital·observational·Posted Jun 25, 2021·Updated Mar 11, 2025

In Brief

An observational study evaluating Epidural analgesia for Epidural Analgesia and 2 related conditions. Completed, enrolled 1,051 participants across 8 sites.

Detailed Summary

Women who receive epidural analgesia during labor are more likely to develop fever than those who do not. Maternal fever during labor can produce various harmful effects on both mothers and infants. The investigators speculate that the effect of epidural analgesia is associated with the development of maternal fever, i.e., better analgesia is associated with higher risk of maternal fever.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsEpidural Analgesia, Analgesic Effect, Fever
CountriesChina
CollaboratorsGuangdong Women and Children Hospital, Tangshan Maternal and Child Health Hospital, Dongguan Maternal and Children Health Hospital, Beijing Haidian Maternal and Child Health Hospital, Beijing Fuxing Hospital, The Fourth Hospital of Shijiazhuang, Xiamen Maternity & Child Care Hospital

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJun 25, 2021
Enrollment StartJun 10, 2021
Primary CompletionFeb 5, 2022
Study CompletionMar 21, 2022
TodayJul 1, 2026
Enrollment to primary: 8 monthsPosted 5.0 years ago

Interventions

Epidural analgesiadrug

Epidural analgesia is performed with a mixture of local anesthetics (ropivacaine) and opioids (sufentanil).