CI

At a glance

ClinicalIndex Comparison Record
Phase 1Recruiting· 50 target
Drug / intervention
CpG-ODNcombination
Likely dose
Not stated in record
Key inclusion· 3
  • Advanced solid malignant tumors
  • Age 18-80 years
  • Life expectancy greater than 3 months
Key exclusion· 4
  • Benign tumors
  • Serious medical comorbidity
  • Life expectancy less than 3 months
  • Other unspecified exclusions

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04952272
NCT04952272Phase 1RecruitingOn TrackUpdated 24mo ago
Long Recruiting

Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Released by Interventional Approaches for Advanced Solid Tumors

Second Affiliated Hospital of Guangzhou Medical University·interventional·Posted Jul 7, 2021·Updated Jun 26, 2024

In Brief

A Phase 1 clinical trial evaluating CpG-ODN for Lung Cancer and 2 related conditions. Currently recruiting, targeting 50 participants across 1 site.

Detailed Summary

To study the safety and clinical effects of intratumor injecting CpG-ODN and in situ release of tumor antigen by interventional ablation or drug-eluting beads to treat advanced solid tumors.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina

Timeline

Phase 1Recruiting
2021202220232024202520262027202820292030203120322033203420352036
First PostedJul 7, 2021
Enrollment StartMar 1, 2021
Primary CompletionJun 30, 2029
Study CompletionJun 30, 2036
TodayJul 1, 2026
Enrollment to primary: 8.3 yearsPosted 5.0 years agoPrimary completion in 3.0 years

Interventions

CpG-ODNcombination

CAR-T cells secreting scFv against OX40