CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 34 enrolled
Drug / intervention
Chidamide +1 moredrug
Likely dose
Chidamide 20mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05068427
NCT05068427Phase 2Completed

A Phase II Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced Non-Small Cell Lung Cancer(NSCLC).

Chipscreen Biosciences, Ltd.·interventional·Posted Oct 5, 2021·Updated Aug 7, 2024

In Brief

A Phase 2 clinical trial evaluating Chidamide and Envafolimab for Non Small Cell Lung Cancer. Completed, enrolled 34 participants across 12 sites.

Detailed Summary

This study is to evaluate the preliminary efficacy and safety of Chidamide combined with Envafolimab in patients with PD-1 inhibitor resistant advanced NSCLC.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedOct 5, 2021
Enrollment StartNov 23, 2021
Primary CompletionFeb 23, 2023
Study CompletionMay 16, 2024
TodayJul 1, 2026
Enrollment to primary: 1.3 yearsPosted 4.7 years ago

Interventions

Chidamidedrug

20mg or 30mg orally twice per week(BIW)

Envafolimabdrug

400mg subcutaneous infusions every 4 weeks