CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 28 enrolled
Drug / intervention
Best Practice +4 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05077072
NCT05077072Phase 2Active

Opioid-Sparing Interdisciplinary Interventions Addressing Pain in Head and Neck Cancer Patients

M.D. Anderson Cancer Center·interventional·Posted Oct 13, 2021·Updated May 4, 2026

In Brief

A Phase 2 clinical trial evaluating Best Practice, Counseling, and 3 other interventions for Head and Neck Carcinoma. Active but no longer recruiting, targeting 28 participants across 1 site.

Detailed Summary

This phase II trial compares different pain management interventions (standard of care \[SOC\], neurofeedback \[NFB\] training, and compassionate high alert team \[CHAT\]) in patients diagnosed with head and neck cancer who are at risk of developing non-medical opioid use (NMOU). The current standard treatment includes regular clinic visits and supportive care and counseling (including topics like patient-doctor communication, cancer care goals, financial issues counseling, and other topics). NFB training is a type of therapy that uses an electroencephalograph (EEG) and a computer software program to measure brain wave activity. The goal of NFB is to help teach patients with pain how to change their own brain waves to lower their feelings of pain and help improve their quality of life. CHAT is a supportive care intervention that includes symptom and pain management, counseling (about pain, symptoms, opioid use and safety, stress, and quality of life), and support for patients and their family members. NFB and CHAT may help to manage pain and lower patient use of opioids.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
202220232024202520262027
First PostedOct 13, 2021
Enrollment StartOct 8, 2021
Primary CompletionOct 31, 2027
TodayJul 1, 2026
Enrollment to primary: 6.1 yearsPosted 4.7 years agoPrimary completion in 1.3 years

Interventions

Best Practiceother

Receive SOC

Counselingother

Participate in CHAT counseling intervention

Electroencephalographyprocedure

Undergo EEG

Neurofeedbackbehavioral

Undergo NFB intervention

Questionnaire Administrationother

Ancillary studies