CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 120 target
Drug / intervention
Plant-based Intervention Groupbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05175248
NCT05175248N/ARecruitingOn TrackUpdated 2mo ago
Long Recruiting
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A Randomized Controlled Trial of a Nutritional Intervention for Endometriosis

Physicians Committee for Responsible Medicine·interventional·Posted Jan 3, 2022·Updated Apr 23, 2026

In Brief

A clinical study evaluating Plant-based Intervention Group for Endometriosis. Currently recruiting, targeting 120 participants across 1 site.

Detailed Summary

In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome composition, and hormonal changes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEndometriosis
CountriesUnited States
Collaborators--

Timeline

N/ARecruiting
202220232024202520262027202820292030
First PostedJan 3, 2022
Enrollment StartMar 2, 2022
Primary CompletionDec 1, 2029
TodayJul 1, 2026
Enrollment to primary: 7.7 yearsPosted 4.5 years agoPrimary completion in 3.4 years

Interventions

Plant-based Intervention Groupbehavioral

Participants in the intervention group will be instructed in ways to adopt a plant-based diet, use appropriate methods of food preparation, and make meals enjoyable and appetizing. The plant-based diet primarily emphasizes whole grains, vegetables, beans and legumes, and fruits. Animal products and added oils will be proscribed and the use of ultra-processed foods, sugar, and sugar-sweetened beverages will be discouraged. Fat intake will be limited to 20-30 g/day.