CI

At a glance

ClinicalIndex Comparison Record
Phase 2Unknown· 495 target
Drug / intervention
UNAIR Inactivated COVID-19 Vaccine +1 morebiological
Likely dose
UNAIR Inactivated COVID-19 Vaccine 1 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05226429
NCT05226429Phase 2Unknown

Safety and Immunogenicity of UNAIR Inactivated COVID-19 Vaccine in Healthy Populations Aged 18 Years and Above (Phase I/II)

Dr. Soetomo General Hospital·interventional·Posted Feb 7, 2022·Updated Jun 15, 2023

In Brief

A Phase 2 clinical trial evaluating UNAIR Inactivated COVID-19 Vaccine and CoronaVac Biofarma COVID-19 Vaccine for COVID-19 Pandemic and Vaccine Reaction. Targeting 495 participants across 1 site.

Detailed Summary

This is a randomized, observer blind, controlled phase I/II study to evaluate the Safety, Reactogenicity, and Immunogenicity of UNAIR Inactivated Covid-19 Vaccine in Healthy Populations Aged 18 Years and Above. UNAIR Inactivated Covid-19 Vaccine is an inactivated vaccine developed by Airlangga University (Universitas Airlangga / UNAIR) made of SARS-CoV-2 virus isolated from a patient in Surabaya, Indonesia, composed with aluminium hydroxy gel, tween 80, and L-histidine. This study will be the first in human.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndonesia

Timeline

Phase 2UnknownOverdue
20222023202420252026
First PostedFeb 7, 2022
Enrollment StartFeb 8, 2022
Primary CompletionApr 6, 2023
Study CompletionJul 6, 2023
TodayJul 1, 2026
Enrollment to primary: 1.2 yearsPosted 4.4 years ago

Interventions

UNAIR Inactivated COVID-19 Vaccinebiological

UNAIR Inactivated Covid-19 Vaccine contains S protein of SARS-CoV-2 virus, Aluminium hydroxide gel, 10 mM L-Histidine buffer, 0.005% Tween Polysorbate 80, and 0.9% Sodium chloride. Vaccine will be prepared in vial (1 ml per vial). One vial will be used for one injection only. The vial should be shaken well before injection.

CoronaVac Biofarma COVID-19 Vaccinebiological

Control vaccine in this study is existing CoronaVac-BioFarma inactivated COVID-19 vaccine which has been used widely in Indonesia.