CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 264 target
Drug / intervention
Gemcitabine +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05352321
NCT05352321N/ARecruitingUpdate OverdueUpdated 48mo ago · Completion was 13mo ago
Enrollment Stalled
Long Recruiting
Update Overdue

Multicenter Randomized Controlled Trial of Surgery Plus Target-reduction Chemoradiotherapy vs Regular Chemoradiotherapy for Newly Diagnosed Resectable Nasopharyngeal Carcinoma

Sun Yat-sen University·interventional·Posted Apr 28, 2022·Updated Jul 1, 2022

In Brief

A clinical study evaluating Gemcitabine, Cisplatin, and 3 other interventions for Nasopharyngeal Carcinoma. Currently recruiting, targeting 264 participants across 2 sites.

Signals

Enrollment appears stalled

Detailed Summary

Through a prospective clinical trial, we intend to combine surgery, induction chemotherapy, target-reduction intensity-modulated radiotherapy and concurrent chemotherapy as an experimental treatment for patients with newly diagnosed resectable nasopharyngeal carcinoma to illuminate whether combined surgery could bring patients better local-regional control and lower adverse reactions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ARecruiting
202320242025202620272028
First PostedApr 28, 2022
Enrollment StartJun 1, 2022
Primary CompletionJun 1, 2025
Study CompletionJun 1, 2028
TodayJul 1, 2026
Enrollment to primary: 3 yearsPosted 4.2 years ago

Interventions

Gemcitabinedrug

for induction chemotherapy

Cisplatindrug

for induction and concurrent chemotherapy

regular intensity-modulated radiotherapyradiation

in active comparator arm

surgeryprocedure

in experimental arm

Target-reduction intensity-modulated radiotherapyradiation

in experimental arm