CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
Aerobic exercise with Blood flow restriction +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05411640
NCT05411640N/ACompleted

Effect of Blood Flow Restriction Training on Glycemic Control, Functional Activity and Quality of Life in Individuals With Prediabetes

Riphah International University·interventional·Posted Jun 9, 2022·Updated Feb 21, 2025

In Brief

A clinical study evaluating Aerobic exercise with Blood flow restriction, Aerobic exercise without Blood flow restriction, and 1 other intervention for PreDiabetes. Completed, enrolled 60 participants across 1 site.

Detailed Summary

The aim of this study is to determine the effects of blood flow restriction training on glycemic control and functional activity in participants with prediabetes. Moreover, This study determine the effects of blood flow restriction training on quality of life in participants with prediabetes

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPreDiabetes
CountriesPakistan
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedJun 9, 2022
Enrollment StartJul 1, 2022
Primary CompletionDec 1, 2022
Study CompletionDec 1, 2023
TodayJul 1, 2026
Enrollment to primary: 5 monthsPosted 4.1 years ago

Interventions

Aerobic exercise with Blood flow restrictionother

Experimental group will be given aerobic exercises with blood flow restriction training. For first four weeks, aerobic exercise will be performed for 25 min with 60-65 % of the maximum heart rate reserve (MHRR). During second four weeks, time of exercise will be 30 min with intensity 60-65% of the MHRR, and for third four weeks, time will be increased to 35 min and intensity will be raised up to 70-75% of the MHRR. . Arterial occlusion of 60% will be achieved by Blood Flow Restriction apparatus. Total intervention protocol for this group will be given for 12 weeks of duration 4 sessions per week with total 48 sessions.

Aerobic exercise without Blood flow restrictionother

Active Comparator group will be given aerobic exercises. For first four weeks, aerobic exercise will be performed for 25 min with 60-65 % of the maximum heart rate reserve (MHRR). During second four weeks, time of exercise will be 30 min with intensity 60-65% of the MHRR, and for third four weeks, time will be increased to 35 min and intensity will be raised up to 70-75% of the MHRR. Total intervention protocol for this group will be given for 12 weeks of duration 4 sessions per week with total 48 sessions.

Patient Education and dietary modificationother

Participants will individually instruct to reduce total energy intake and increase physical activity, aiming at a 5% reduction in body weight. The participants will be given pamphlets providing general information on pre diabetes and dietary modifications. Total intervention protocol for the group will be given for 12 weeks of duration 4 sessions per week with total 48 sessions.