CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 80 enrolled
Drug / intervention
Real Acupuncture +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05458284
NCT05458284Phase 2Active

Acupuncture for Taxane-Induced Peripheral Neuropathy Prevention (ATP): A Phase II Randomized, Placebo Controlled Trial

Memorial Sloan Kettering Cancer Center·interventional·Posted Jul 14, 2022·Updated Aug 27, 2025

In Brief

A Phase 2 clinical trial evaluating Real Acupuncture and Sham Acupuncture for Breast Cancer and Taxane-Induced Peripheral Neuropathy. Active but no longer recruiting, targeting 80 participants across 7 sites.

Detailed Summary

Some people experience a side effect while they are receiving taxane called taxane-induced peripheral neuropathy (TIPN). TIPN is pain in the arms and legs due to nerve damage caused by cancer treatment and may interfere with quality of life. The purpose of this study is to learn if acupuncture can prevent TIPN from getting worse. Acupuncture is a medical technique that involves insertion of very thin needles into specific areas on the body. We will compare real acupuncture (RA) to placebo (sham) acupuncture (SA). SA is done like RA, but will use different needles and target different sites or places on the body than RA. We are comparing RA to SA to learn whether RA can prevent TIPN from getting worse while receiving taxane.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2ActiveOverdue
2023202420252026
First PostedJul 14, 2022
Enrollment StartJul 11, 2022
Primary CompletionJul 1, 2026
TodayJul 1, 2026
Enrollment to primary: 4.0 yearsPosted 4.0 years ago

Interventions

Real Acupunctureprocedure

Real Acupuncture weekly till taxane completion

Sham Acupunctureother

Sham Acupuncture weekly till taxane completion