CI

At a glance

ClinicalIndex Comparison Record
N/ATerminated· 8 enrolled
Drug / intervention
Unipolar Polarity Switch Left +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05464537
NCT05464537N/ATerminated
Terminated

To Assess the Efficacy Rate of Unipolar Polarity Switch for Lesion Assessment in Pulmonary Vein Isolation

Kansas City Heart Rhythm Research Foundation·interventional·Posted Jul 19, 2022·Updated Mar 5, 2025

In Brief

A clinical study evaluating Unipolar Polarity Switch Left and Unipolar Polarity Switch Right for Atrial Fibrillation. Terminated early, enrolled 8 participants across 2 sites.

Signals

Trial was terminated early

Detailed Summary

The technique of intraprocedural electrogram morphology as a measure of lesion effectiveness in an attempt to achieve durable PVI, clearly led to shortened procedural time, radiation exposure, and superiority in outcomes, with the implementation of a reproducible, readily available intraprocedural tool that can be applied universally.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ATerminatedFinished
2023202420252026
First PostedJul 19, 2022
Enrollment StartAug 28, 2023
Primary CompletionNov 27, 2024
TodayJul 1, 2026
Enrollment to primary: 1.2 yearsPosted 3.9 years ago

Interventions

Unipolar Polarity Switch Leftother

10-15 Left veins are randomized to Unipolar Polarity Shift, right veins are randomized to CAI-OPR-LAAP

Unipolar Polarity Switch Rightother

10-15 cases randomized to CAI-OPR-LAAP on left veins, and Unipolar Polarity Switch on right veins