CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 50 enrolled
Drug / intervention
Ipilimumab +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05501054
NCT05501054Phase 2Active

Phase 1b/2 Trial of Ipilimumab, Nivolumab, and Ciforadenant (Adenosine A2a Receptor Antagonist) in First-line Advanced Renal Cell Carcinoma.

M.D. Anderson Cancer Center·interventional·Posted Aug 15, 2022·Updated Jan 14, 2026

In Brief

A Phase 2 clinical trial evaluating Ipilimumab, Nivolumab, and 1 other intervention for Renal Cell Carcinoma. Active but no longer recruiting, targeting 50 participants across 3 sites.

Detailed Summary

To learn if the combination of ciforadenant, ipilimumab, and nivolumab can help to control advanced renal cell carcinoma

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
2023202420252026
First PostedAug 15, 2022
Enrollment StartFeb 9, 2023
Primary CompletionNov 1, 2026
TodayJul 1, 2026
Enrollment to primary: 3.7 yearsPosted 3.9 years agoPrimary completion in 4 months

Interventions

Ipilimumabdrug

Given by IV (vein)

Nivolumabdrug

Given by IV (vein)

Ciforadenantdrug

Given by PO