CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 1 target
Drug / intervention
Soy proteinother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05638061
NCT05638061N/AActiveUpdate OverdueUpdated 25mo ago · Completion was 21mo ago
Enrollment Stalled

The Effect of Food Sources of Soy Protein on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

University of Toronto·observational·Posted Dec 6, 2022·Updated May 6, 2024

In Brief

An observational study evaluating Soy protein for Blood Pressure and Cardiovascular Diseases. Active but no longer recruiting, targeting 1 participant across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

Hypertension is one of the leading risk factors for death and significantly increases the risk for cardiovascular (CVD), brain and kidney diseases. It is also one of the leading modifiable risk factors for CVD, which also plays a significant role in the global burden of death and disease. Dietary guidelines for blood pressure management and hypertension emphasize fruits and vegetables, plant-based proteins and foods low in saturated fat. With the growing interest in plant-based alternatives and plant-based diets, there is a need to clarify their benefits on blood pressure. Soy protein is a complete protein and is the only plant-based beverage alternative that is comparable to dairy milk. There are mixed findings on the effects of soy on blood pressure due to differences in study design and subjects. To better address this question and inform public health guidelines the investigators will conduct a systematic review and meta-analysis of randomized controlled trials of the effect of soy protein on reducing blood pressure in individuals with and without hypertension.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesCanada
Collaborators--

Timeline

N/AActiveOverdue
2023202420252026
First PostedDec 6, 2022
Enrollment StartOct 1, 2022
Primary CompletionSep 1, 2024
Study CompletionDec 1, 2024
TodayJul 1, 2026
Enrollment to primary: 1.9 yearsPosted 3.6 years ago

Interventions

Soy proteinother

Soy foods or isolated soy protein