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NCT05638061N/AActiveUpdate OverdueUpdated 25mo ago · Completion was 21mo agoThe Effect of Food Sources of Soy Protein on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
In Brief
An observational study evaluating Soy protein for Blood Pressure and Cardiovascular Diseases. Active but no longer recruiting, targeting 1 participant across 1 site.
Signals
Detailed Summary
Hypertension is one of the leading risk factors for death and significantly increases the risk for cardiovascular (CVD), brain and kidney diseases. It is also one of the leading modifiable risk factors for CVD, which also plays a significant role in the global burden of death and disease. Dietary guidelines for blood pressure management and hypertension emphasize fruits and vegetables, plant-based proteins and foods low in saturated fat. With the growing interest in plant-based alternatives and plant-based diets, there is a need to clarify their benefits on blood pressure. Soy protein is a complete protein and is the only plant-based beverage alternative that is comparable to dairy milk. There are mixed findings on the effects of soy on blood pressure due to differences in study design and subjects. To better address this question and inform public health guidelines the investigators will conduct a systematic review and meta-analysis of randomized controlled trials of the effect of soy protein on reducing blood pressure in individuals with and without hypertension.
Study Details
Timeline
Interventions
Soy foods or isolated soy protein