CI

At a glance

ClinicalIndex Comparison Record
N/AEnrolling by Invitation· 426 target
Drug / intervention
Supported dCBT +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05746767
NCT05746767N/AEnrolling by InvitationOn Track
CompareCT.gov

SUPERA: Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Safety-Net Patients in Primary Care

University of California, Irvine·interventional·Posted Feb 28, 2023·Updated May 19, 2026

In Brief

A clinical study evaluating Supported dCBT and Unsupported dCBT for Depression, Anxiety. Currently enrolling by invitation, targeting 426 participants across 11 sites.

Detailed Summary

Investigators will evaluate the implementation of an evidence-based, Spanish-language, digital, cognitive-behavioral therapy intervention (SilverCloud) in primary care settings for Latino patients with depression and/or anxiety. 426 participants will be enrolled in a two-armed trial comparing self-guided vs. supported dCBT (SilverCloud). At the provider level, investigators will compare the efficacy of provider referrals with the use of a clinic patient registry to identify candidates who could benefit from a digital mental health intervention.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression, Anxiety
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH), University of California, Berkeley, University of California, San Francisco, University of California, Riverside, University of New Mexico, University of Arizona

Timeline

N/AEnrolling by Invitation
20242025202620272028
First PostedFeb 28, 2023
Enrollment StartMar 14, 2024
Primary CompletionDec 31, 2027
Study CompletionMar 31, 2028
TodayJul 1, 2026
Enrollment to primary: 3.8 yearsPosted 3.3 years agoPrimary completion in 1.5 years

Interventions

Supported dCBTbehavioral

In the supported dCBT condition, each patient will receive complete access to the SilverCloud platform. In addition, patients will be assigned a supporter who will provide regular support based on an established coaching support protocol. Supporters will conduct a brief engagement call (30-40 minutes) to provide an overview of SilverCloud, identify goals, and set expectations, introduce themselves, and orient the participant to the role of the peer supporter. Supporters will then provide weekly check-ins through phone calls or messaging. Participants will be able to communicate with the supporters through the platform through messaging or sharing activities for additional discussion. The major goal of the support is to promote use of the platform.

Unsupported dCBTbehavioral

Unsupported dCBT provides all features of the SilverCloud platform with the exception of support features (structured interactions with supporter and share features). Patients will be provided complete access to SilverCloud and instructed to use it for 8-weeks. Patients will receive weekly automated messages to encourage engagement.