At a glance
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Efficacy and Safety of Saline Rinses Combined With Steroid-Eluting Stent Implant or Steroid Nasal Spray in Radiation-Related Sinusitis
In Brief
A Phase 3 clinical trial evaluating Steroid-eluting stent implantation, Steroid nasal spray, and 1 other intervention for Radiation-Induced Mucositis. Targeting 168 participants across 1 site.
Detailed Summary
Sinusitis is one of the most common sequelae after radiotherapy among nasopharyngeal carcinoma patients. While local steroids have been shown to be effective in the management of patients with chronic rhinosinusitis, their role in treating radiation-related sinusitis is ambiguous. Poor adherence to nasal steroid spray often contributes to the failure of symptom relief. The aim of this study is to determine if steroids stents implantation into the sinuses could improve patient outcomes in radiation-related sinusitis.
Study Details
Timeline
Interventions
The sinus cavity with inflammation receives one bioabsorbable steroid-eluting sinus stent.
1 spray into each nostril once a day.
The saltwater runs through nasal passages and drains out of the nostril.