At a glance
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Single-Group Crossover Trial Comparing Behavioral Treatment to Memantine in Body Focused Repetitive Behaviors
In Brief
A Phase 3 clinical trial evaluating Memantine and ComB Behavioral Therapy for Skin-Picking and Trichotillomania (Hair-Pulling Disorder). Active but no longer recruiting, targeting 26 participants across 1 site.
Detailed Summary
The goal of the proposed study is to compare the efficacy of behavioral treatment (BT) to memantine, a psychopharmacological agent, for BFRBs. 28 subjects with trichotillomania (TTM) or skin picking disorder (SPD) will receive 8 weeks of memantine treatment, followed by 8 weeks of comprehensive behavioral therapy (ComB) treatment. The hypothesis to be tested is that behavioral therapy will be associated with superior clinical outcomes as compared to memantine. A second hypothesis is that both memantine and behavioral therapy will demonstrate improvement from baseline to the respective posttreatment assessment.
Study Details
Timeline
Interventions
Cognition-enhancing medication
Therapy for BFRBs