CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 233 enrolled
Drug / intervention
Whole-Course Multidisciplinary Care Interventionbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05828004
NCT05828004N/ACompleted

Effect of Multidisciplinary Team Support on Head and Neck Cancer Patients Receiving Radiotherapy: The SHINE-MDT Randomized Controlled Trial

West China Hospital·interventional·Posted Apr 25, 2023·Updated Aug 28, 2025

In Brief

A clinical study evaluating Whole-Course Multidisciplinary Care Intervention for Head and Neck Carcinoma and Radiotherapy Side Effects. Completed, enrolled 233 participants across 1 site.

Detailed Summary

Radiotherapy is one of the main treatments for head and neck Carcinoma. The incidence of radiotherapy-related adverse events is greater than 90%, and severe adverse events may lead to the interruption of radiotherapy. The management of nutritional, psychological, and rehabilitative issues in patients undergoing radiotherapy for head and neck cancer presents unique clinical challenges. We aimed to evaluate the efficacy of the SHINE-MDT (Supportive Holistic Interventions by Nurses and Experts via Multidisciplinary Team) in reducing radiotherapy interruptions and improving patients' quality of life (QoL) compared with usual care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedApr 25, 2023
Enrollment StartApr 27, 2023
Primary CompletionDec 1, 2023
Study CompletionJun 1, 2024
TodayJul 1, 2026
Enrollment to primary: 7 monthsPosted 3.2 years ago

Interventions

Whole-Course Multidisciplinary Care Interventionbehavioral

On the basis of standard treatment, all patients were evaluated by senior practice nurses in the Department of Oncology in person at the time of enrollment (before radiotherapy) and once every week during radiotherapy, and once in person/over the phone at 1, 2, 3, and 6 months after radiotherapy.