CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 216 target
Drug / intervention
AK127 in combination with AK112drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05951608
NCT05951608Phase 2ActiveMonitorUpdated 2mo ago · Completion was 2mo ago
Slow Enrollment

A Phase Ib/II Open-label Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK112 in Patients With Advanced Malignant Tumors

Akeso·interventional·Posted Jul 19, 2023·Updated Apr 23, 2026

In Brief

A Phase 2 clinical trial evaluating AK127 in combination with AK112 for Advanced Solid Tumors. Active but no longer recruiting, targeting 216 participants across 1 site.

Signals

Enrolling slower than its timeline implies

Detailed Summary

A Phase Ib/II Open-label Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of AK127 in combination with AK112 in Patients with Advanced Malignant Tumors

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2Active
202420252026
First PostedJul 19, 2023
Enrollment StartOct 16, 2023
Primary CompletionMay 1, 2026
Study CompletionAug 15, 2026
TodayJul 1, 2026
Enrollment to primary: 2.5 yearsPosted 2.9 years ago

Interventions

AK127 in combination with AK112drug

AK127 in combination with AK112 (administered on Day 1 of each cycle, Q3W) up to 2 years