CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 139 target
Drug / intervention
PLB1004drug
Likely dose
PLB1004 80mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06015503
NCT06015503Phase 2ActiveUpdate OverdueCompletion was 15mo ago
Enrollment Stalled

A Phase Ⅱ,Open-label, Single-line, Multiple Cohorts, Multicenter Study Assessing the Safety and Efficacy of PLB1004 in EGFR ex20ins Mutation Patients With Advanced and Metastatic Non-small Cell Lung Cancer(NSCLC)

Avistone Biotechnology Co., Ltd.·interventional·Posted Aug 29, 2023·Updated May 22, 2026

In Brief

A Phase 2 clinical trial evaluating PLB1004 for NSCLC (Non-small Cell Lung Cancer). Active but no longer recruiting, targeting 139 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

It is a phase Ⅱ,open-label, single-line, Multiple cohorts, Multicenter study assessing the Safety and Efficacy of PLB1004 in EGFR ex20ins mutation patients with Advanced and Metastatic Non-small Cell Lung Cancer(NSCLC).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2Active
2024202520262027
First PostedAug 29, 2023
Enrollment StartJul 21, 2023
Primary CompletionMar 6, 2025
Study CompletionDec 30, 2026
TodayJul 1, 2026
Enrollment to primary: 1.6 yearsPosted 2.8 years ago

Interventions

PLB1004drug

PLB1004 is a capsule in the form of 80mg and 40mg.