At a glance
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Washed Microbiota Transplantation (WMT) for Autism Spectrum Disorder (ASD)
In Brief
A Phase 1 clinical trial evaluating Washed Microbiota Transplantation for Autism Spectrum Disorder. Currently recruiting, targeting 80 participants across 2 sites.
Signals
Detailed Summary
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD traits. Intestinal microbial disturbance is common in children with ASD. A great deal of evidence shows that intestinal microbes can influence the brain to play its role through "gut-brain-microbiota axis". We intend to explore the role of Washed Microbiota Transplantation in improving symptoms of children in ASD with or without ADHD; To study the potential etiological mechanism of WMT for the neurodevelopmental disorders.
Study Details
Timeline
Interventions
The prepared microbiota suspension was infused into the participates' lower gut.