CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
LF-rTMS +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06064747
NCT06064747N/ACompleted
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Low-Frequency REpetitive TRanscranial Magnetic Stimulation Combined With Endovascular Treatment in ACute Ischemic StrokE (RETRACE-II): A Randomized, Double-Blind, Sham-Controlled, Phase 2 Pilot Trial

Beijing Tiantan Hospital·interventional·Posted Oct 3, 2023·Updated Apr 8, 2026

In Brief

A clinical study evaluating LF-rTMS and Sham stimulation for Stroke, Acute Ischemic. Completed, enrolled 60 participants across 1 site.

Detailed Summary

This is a multicenter, randomized, double-blind, sham-controlled, investigator-initiated clinical study, to evaluate the clinical efficacy and safety of LF-rTMS in rescuing the ischemic penumbra, reducing disability rate and improving functional outcome in patients with acute ischemic stroke receiving early endovascular recanalization (bridging or direct endovascular therapy)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke, Acute Ischemic
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedOct 3, 2023
Enrollment StartMay 25, 2024
Primary CompletionApr 15, 2025
Study CompletionJul 2, 2025
TodayJul 1, 2026
Enrollment to primary: 11 monthsPosted 2.7 years ago

Interventions

LF-rTMSdevice

LF-rTMS group: using "8" coil,1-Hz rTMS to stimulate the M1 region of the ipsilateral hemisphere, the stimulation intensity was RMT 100%, 1200pulses/session, two sessions (2400 pulses)/day (interval ≥ 2 hours), lasting 3 days (total 6 sessions, 7200pulses);

Sham stimulationdevice

Sham stimulation group: the sham stimulation coil was used to stimulate the same site, duration and sound as the LF-rTMS group, ensuring no effective stimulation, twice a day for 3 days.