CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 100 target
Drug / intervention
Left Atrial Appendage Occlusionother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06075628
NCT06075628N/ARecruitingUpdate OverdueUpdated 10mo ago · Completion was 6mo ago
Enrollment Stalled
Update Overdue
CompareCT.gov

Long-Term Outcomes of Left Atrial Appendage Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry

Kansas City Heart Rhythm Research Foundation·observational·Posted Oct 10, 2023·Updated Aug 28, 2025

In Brief

An observational study evaluating Left Atrial Appendage Occlusion for Atrial Fibrillation and Ischemic Stroke, Acute. Currently recruiting, targeting 100 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

This study is intended to assess the incidence and correlation to the development of peri-device leaks (PDLs), device related thrombosis (DRTs) and cerebral vascular accident (CVA)/transient ischemic attacks (TIAs) in association with left atrial appendage contrast flow (LAA-CF). It will be a multi-center, retrospective study. Approximately 100 subject charts will be reviewed.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsAtrial Fibrillation, Ischemic Stroke, Acute
CountriesUnited States
Collaborators--

Timeline

N/ARecruitingOverdue
202420252026
First PostedOct 10, 2023
Enrollment StartJul 24, 2023
Primary CompletionDec 1, 2025
TodayJul 1, 2026
Enrollment to primary: 2.4 yearsPosted 2.7 years ago

Interventions

Left Atrial Appendage Occlusionother

Acute ischemic stroke is a major cause of morbidity and mortality in non-valvular Atrial Fibrillation (AF). Oral Anticoagulation (OAC) with Warfarin and Direct oral anticoagulants (DOACs) has been the mainstay to prevent systemic thromboembolism (STE) in this patient population. It is estimated that around 50% of patients who have AF with indication for OAC end up being not on OAC due to bleeding complications leaving them at high risk for developing STE. Left atrial appendage occlusion (LAAO) offers an option in such population.