CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 3 target
Drug / intervention
ARC-BSI Lumbar systemdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06243952
NCT06243952N/AActiveOn Track

Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb Rehabilitation

Ecole Polytechnique Fédérale de Lausanne·interventional·Posted Feb 6, 2024·Updated Jun 11, 2026

In Brief

A clinical study evaluating ARC-BSI Lumbar system for Spinal Cord Injuries and Paraplegia. Active but no longer recruiting, targeting 3 participants across 1 site.

Detailed Summary

The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with lumbar targeted epidural electrical stimulation (EES) of the spinal cord to restore voluntary motor functions of lower limbs in participants with chronic spinal cord injury suffering from mobility impairment. The goal is to establish a direct bridge between the motor intention of the participant and the the spinal cord below the lesion, which should not only improve or restore voluntary control of legs movement and support immediate locomotion, but also promote neurological recovery when combined with neurorehabilitation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSwitzerland
Collaborators--

Timeline

N/AActive
2024202520262027202820292030
First PostedFeb 6, 2024
Enrollment StartMay 3, 2024
Primary CompletionJul 1, 2030
TodayJul 1, 2026
Enrollment to primary: 6.2 yearsPosted 2.4 years agoPrimary completion in 4 years

Interventions

ARC-BSI Lumbar systemdevice

Implantation of a 64 channel - ECoG array over the sensory motor cortex of the lower limbs, combined with an implantation of 16 channel spinal cord stimulation system over the lumbar region. The decoded motor intentions are driving the implanted spinal cord stimulation system. Brain-controlled spinal cord stimulation is used for training and rehabilitation to recover voluntary movements.