CI

At a glance

ClinicalIndex Comparison Record
Phase 3Recruiting· 150 target
Drug / intervention
SPOT-ON Early Start +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06336642
NCT06336642Phase 3RecruitingOn TrackUpdated 3mo ago
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Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology

M.D. Anderson Cancer Center·interventional·Posted Mar 29, 2024·Updated Mar 10, 2026

In Brief

A Phase 3 clinical trial evaluating SPOT-ON Early Start and SPOT-ON Delayed Start for Dyspnea. Currently recruiting, targeting 150 participants across 1 site.

Detailed Summary

To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDyspnea
CountriesUnited States
Collaborators--

Timeline

Phase 3Recruiting
20252026202720282029203020312032
First PostedMar 29, 2024
Enrollment StartJun 11, 2024
Primary CompletionMar 31, 2030
Study CompletionMar 31, 2032
TodayJul 1, 2026
Enrollment to primary: 5.8 yearsPosted 2.3 years agoPrimary completion in 3.8 years

Interventions

SPOT-ON Early Startbehavioral

Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and/or trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.

SPOT-ON Delayed Startbehavioral

Participants will start treatment within 3 days of enrollment, which may include: receiving information on breathing techniques, relaxation techniques, posture techniques, and distraction techniques, and/or trying different oxygen-based therapies, such as high-flow nasal cannula, low-flow supplemental oxygen, and non-invasive ventilation with a respiratory therapist.