CI

At a glance

ClinicalIndex Comparison Record
Phase 2Recruiting· 52 target
Drug / intervention
sunvozertinib in combination with Anlotinibdrug
Likely dose
sunvozertinib in combination with Anlotinib 300 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06348927
NCT06348927Phase 2RecruitingUpdate OverdueUpdated 21mo ago · Completion was 8mo ago
Enrollment Stalled
Update Overdue

A Phase II, Single-Arm Study Evaluating the 1st Line Efficacy and Safety of Sunvozertinib Plus Anlotinib in EGFR-Sensitive Mutations Combined With Co-Mutations Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) (WUKONG-32)

Hunan Province Tumor Hospital·interventional·Posted Apr 5, 2024·Updated Sep 19, 2024

In Brief

A Phase 2 clinical trial evaluating sunvozertinib in combination with Anlotinib for Non-Small Cell Lung Cancer. Currently recruiting, targeting 52 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

This is a phase II, open-label, single-arm, single-center clinical study to evaluate the preliminary efficacy of sunvozertinib in combination with anlotinib in patients with EGFR-sensitive mutations and co-mutations in locally advanced or metastatic treatment-naive non-small cell lung cancer. Condition or disease Intervention/treatment Phase Non-Small Cell Lung Cancer Drug: sunvozertinib Drug: anlotinib Phase 2

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2Recruiting
202520262027
First PostedApr 5, 2024
Enrollment StartJul 1, 2024
Primary CompletionOct 31, 2025
Study CompletionApr 30, 2027
TodayJul 1, 2026
Enrollment to primary: 1.3 yearsPosted 2.2 years ago

Interventions

sunvozertinib in combination with Anlotinibdrug

Drug: Sunvozertinib combination with Anlotinib Sunvozertinib 300 mg once daily (QD) with Anlotinib 8mg once daily (QD in Day 1-14),21 days in one cycle.