At a glance
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Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder and Its Comorbidities
In Brief
A Phase 1 clinical trial evaluating washed microbiota transplantation for Attention-deficit/Hyperactivity Disorder. Currently recruiting, targeting 50 participants across 2 sites.
Detailed Summary
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention and hyperactivity-impulsivity. ADHD is often accompanied by oppositional defiant disorder and sleep disturbance, and can increase the risk of other psychiatric disorders, functional impairment in academic and occupational performance. Recently, gut microbiota has been implicated in the ADHD via gut-brain axis. In this study, investigators aimed to evaluate the efficacy of WMT for core ADHD symptoms and its comorbidities using specialized questionnaires for ADHD and investigate the underlying mechanism.
Study Details
Timeline
Interventions
The prepared microbiota suspension was infused into the participates' lower gut.