At a glance
ClinicalIndex Comparison RecordN/ACompleted· 3 enrolled
Drug / intervention
QH104 Cell injectionbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3+ Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences·interventional·Posted Sep 19, 2024·Updated Jan 29, 2026
In Brief
A clinical study evaluating QH104 Cell injection for Solid Tumor and Meningeal Metastasis. Completed, enrolled 3 participants across 1 site.
Detailed Summary
This is an open, single-arm, single-center, interventional clinical study. It is planned to enroll 3-6 patients with meningeal metastases from B7H3+ solid tumors and to explore, on a small scale, the efficacy of local injection of allogeneic B7H3 CAR-γδ T cells (3\*107/dose) for the treatment of patients with meningeal metastases from B7H3+ solid tumors.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSolid Tumor, Meningeal Metastasis
CountriesChina
Collaborators--
Timeline
N/ACompletedFinished
20252026
Enrollment StartApr 2024
First PostedSep 2024
Primary CompletionMay 2025
Study CompletionJan 2026
TodayJul 2026
First PostedSep 19, 2024
Enrollment StartApr 1, 2024
Primary CompletionMay 31, 2025
Study CompletionJan 28, 2026
TodayJul 1, 2026
Enrollment to primary: 1.2 yearsPosted 1.8 years ago
Interventions
QH104 Cell injectionbiological
Patients will first be pre-screened for B7H3 expression of tumor and exist Meningeal Metastases.