CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Active· 18 target
Drug / intervention
SapRNA™-MICA/B Tumor Vaccinebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06610227
NCT06610227Early Ph 1ActiveUpdate OverdueUpdated 11mo ago · Completion was 9mo ago
Enrollment Stalled

A Clinical Study to Evaluate the Safety, Tolerability, Preliminary Efficacy, and Immunogenicity of the Novel RNA Tumor Vaccine Targeting MICA/B Stress Proteins in Patients With Advanced Solid Tumors

NING LI·interventional·Posted Sep 24, 2024·Updated Jul 16, 2025

In Brief

A Early Phase 1 clinical trial evaluating SapRNA™-MICA/B Tumor Vaccine for Advanced Solid Tumors. Active but no longer recruiting, targeting 18 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

This is an open-label, single-arm study to evaluate the safety and efficacy of multiple doses of SapRNA™-MICA/B Tumor Vaccine in patients with advanced solid tumors. Eligible patients will receive the monotherapy with SapRNA™-MICA/B Tumor Vaccine, which will be administered by intramuscular injection on Day 1, Day 14, and Day 28 respectively. Follow-up visits will be performed as scheduled after the end of treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Early Ph 1ActiveOverdue
20252026
First PostedSep 24, 2024
Enrollment StartNov 8, 2024
Primary CompletionSep 1, 2025
Study CompletionDec 1, 2025
TodayJul 1, 2026
Enrollment to primary: 10 monthsPosted 1.8 years ago

Interventions

SapRNA™-MICA/B Tumor Vaccinebiological

patients will receive the monotherapy with SapRNA™-MICA/B Tumor Vaccine, which will be administered by intramuscular injection on Day 1, Day 14, and Day 28 respectively