CI

At a glance

ClinicalIndex Comparison Record
Phase 4Recruiting· 716 target
Drug / intervention
Alteplase +1 moredrug
Likely dose
Alteplase 0.9 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06653946
NCT06653946Phase 4RecruitingUpdate OverdueUpdated 20mo ago · Completion was 24mo ago
Enrollment Stalled
Long Recruiting
Update Overdue

the Predictors of Different ECASS-based Hemorrhagic Transformation Subtypes in Acute Embolic Stroke Patients Treated With Alteplase

Kafrelsheikh University·interventional·Posted Oct 23, 2024·Updated Oct 29, 2024

In Brief

A Phase 4 clinical trial evaluating Alteplase for Ischemic Stroke and Alteplase Adverse Reaction. Currently recruiting, targeting 716 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

The investigators evaluated the impact of AF on different subtypes of post-alteplase hemorrhagic transformation of brain infarction.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--

Timeline

Phase 4RecruitingOverdue
2023202420252026
First PostedOct 23, 2024
Enrollment StartJul 1, 2022
Primary CompletionJul 1, 2024
Study CompletionNov 1, 2024
TodayJul 1, 2026
Enrollment to primary: 2 yearsPosted 1.7 years ago

Interventions

Alteplasedrug

Following the guidelines set by the American Heart Association/American Stroke Association (AHA/ASA), inclusion and exclusion criteria for alteplase were established; 0.9 mg/kg of alteplase up to a maximum dose of 90 mg was administered intravenously to eligible individuals within 4.5 hours of the beginning of their clinical manifestations (10% bolus, 90% infusion in 1 hour). After receiving IV-alteplase, all patients continued their management and rehabilitation in the stroke unit

Alteplasedrug

Following the guidelines set by the American Heart Association/American Stroke Association (AHA/ASA), inclusion and exclusion criteria for alteplase were established; 0.9 mg/kg of alteplase up to a maximum dose of 90 mg was administered intravenously to eligible individuals within 4.5 hours of the beginning of their clinical manifestations (10% bolus, 90% infusion in 1 hour). After receiving IV-alteplase, all patients continued their management and rehabilitation in the stroke unit