CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 48 enrolled
Drug / intervention
Isometric handgrip exercise training with resistance exercise +1 moreother
Likely dose
Not stated in record
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Search/NCT06658548
NCT06658548N/ACompleted

Effects of Isometric Hand Grip Exercise Training on Lung Function in COPD Patients

Riphah International University·interventional·Posted Oct 26, 2024·Updated Jun 13, 2025

In Brief

A clinical study evaluating Isometric handgrip exercise training with resistance exercise and Resistance Exercise for Chronic Obstructive Pulmonary Disease. Completed, enrolled 48 participants across 1 site.

Detailed Summary

Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable lung disease. People with COPD must work harder to breathe, which can lead to shortness of breath and/or feeling tired. Early in the disease, people with COPD may feel short of breath when they exercise. As the disease progresses, it can be hard to breathe out (exhale) or even breathe in (inhale). A person with COPD may have obstructive bronchiolitis emphysema, or a combination of both conditions. There is variety of treatment like breathing exercises, inspiratory muscle training exercises, resistance training and aerobic exercise to improve lung function as well as to decrease the chances of cardiopulmonary complications. the purpose of this study it to observe the effects of hand gripping isometric exercises on pulmonary functions in COPD patients. Study design will be randomized clinical trial in which experiment group will receive isometric training with resistance training and other group will only receive resistance training . Total forty eight participates will recruited with convince sampling, after that we will use simple random sampling to divide the patient into both equal groups. Digital spirometry will be used to document the pulmonary function also to observe the difference in post treatment.Data analysis will be done using SPSS version 25.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPakistan
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedOct 26, 2024
Enrollment StartSep 1, 2024
Primary CompletionDec 30, 2024
Study CompletionFeb 28, 2025
TodayJul 1, 2026
Enrollment to primary: 4 monthsPosted 1.7 years ago

Interventions

Isometric handgrip exercise training with resistance exerciseother

The subjects will perform 24 consecutive days, an isometric handgrip exercise at 30% Maximum Voluntary Contraction (M.V.C)continue the exercise protocol for another 48 consecutive days.

Resistance Exerciseother

The subjects will undergo outpatient training intervention during a period of 8 weeks will be using a hypertrophic maximum strength training method, which will divided into three phases: (1) muscle habituation training (2 weeks), (2) hypertrophic training I (5 weeks), and (3) hypertrophic training II, with intensified eccentric work (5 weeks).