At a glance
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Establishment of "Xijiang Project" Million-Person Screening Cohort for Nasopharyngeal Carcinoma
In Brief
An observational study evaluating EBV antibodies test, EBV DNA test, and 3 other interventions for Nasopharyngeal Carcinoma (NPC) and Screening. Active but no longer recruiting, targeting 1,000,000 participants across 1 site.
Detailed Summary
The purpose of this study is to establish a comprehensive and integrated nasopharyngeal carcinoma screening cohort, which includes an epidemiological information database containing basic information, gender, age, ethnic and family history, dietary and lifestyle habits, and geographical environmental factors; a biobank of blood, tissue fluid, swabs, etc., for Epstein-Barr virus, tumors, and genetics; a clinical examination database including nasopharyngoscopy, imaging, pathology, and other examinations; and databases of Epstein-Barr virus and human genetic sequencing, etc.
Study Details
Timeline
Interventions
ELISA test of VCA-IgA, EBNA1-IgA, EA-IgA, Zta-IgA, Rta-IgG and P85-Ab in nasopharyngeal brushing and plasma in plasma, saliva and nasopharyngeal brushing.
quantitative polymerase chain reaction, methylation sequencing and target sequencing of EBV DNA in nasopharyngeal brushing, saliva and plasma.
epidemiological information survey including basic conditions, dietary and lifestyle habits, social, geographical, environmental, and other information.
nasopharyngoscopy, head and neck MRI.
EB virus and human genetic sequencing for plasma, etc.