CI

At a glance

ClinicalIndex Comparison Record
Phase 2Recruiting· 50 target
Drug / intervention
ZG005 for Injection +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06903377
NCT06903377Phase 2RecruitingOn TrackUpdated 5mo ago

A Multicenter, Open-label, Dose-Escalation and Dose-Expansion Phase I/II Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer

Suzhou Zelgen Biopharmaceuticals Co.,Ltd·interventional·Posted Mar 30, 2025·Updated Jan 5, 2026

In Brief

A Phase 2 clinical trial evaluating ZG005 for Injection and Gecacitinib Hydrochloride Tablets for Non-small Cell Lung Cancer. Currently recruiting, targeting 50 participants across 1 site.

Detailed Summary

This is a multicenter Phase I/II study for patients with advanced non-small cell lung cancer who have failed PD-1/L1 therapy, aiming to evaluate the safety of ZG005 in combination with Gecacitinib in this population, as well as the preliminary efficacy of this combination regimen.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2Recruiting
20262027
First PostedMar 30, 2025
Enrollment StartMay 23, 2025
Primary CompletionApr 1, 2027
Study CompletionMay 1, 2027
TodayJul 1, 2026
Enrollment to primary: 1.9 yearsPosted 1.3 years agoPrimary completion in 9 months

Interventions

ZG005 for Injectionbiological

intravenous infusion

Gecacitinib Hydrochloride Tabletsdrug

Oral